期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 28, 期 -, 页码 104-109出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2014.03.031
关键词
Ovarian carcinoma; Ovarian surface epithelium; Border cell migration; Follicular epithelium; Hippo pathway
资金
- Spanish Ministerio de Economia y Competitividad
- FEDER programme [BMC2012-35446]
- Junta de Andalucia (Proyecto de Excelencia) [P09-CVI-5058]
- CONSOLIDER programme [CSD-2007-00008]
Considering the degree of detail available at the genetic and cellular levels, the Drosophila ovary stands out as a powerful system to identify new players in the regulation of key aspects of cancer progression. In this review, we will comment on how the use of the Drosophila ovary has helped to elucidate some of the molecular bases of ovarian malignancies and to identify and characterize critical tumour suppressor genes and oncogenes with an impact in human pathologies. (C) 2014 Elsevier Ltd. All rights reserved.
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