期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 32, 期 -, 页码 128-136出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2014.04.036
关键词
Drosophila; Dpp; Morphogen; Scaling; Growth; Patterning; Feedback regulation; Pentagone; Brinker; Spalt; Optomotor blind; Daughters-against-dpp; Dally; Silencer Element; Activating Element
Decapentaplegic (Dpp), the fly homolog of the secreted mammalian BMP2/4 signaling molecules, is involved in almost all aspects of fly development. Dpp has critical functions at all developmental stages, from patterning of the eggshell to the determination of adult intestinal stem cell identity. Here, we focus on recent findings regarding the transcriptional regulatory logic of the pathway, on a new feedback regulator, Pentagone, and on Dpp's roles in scaling and growth of the Drosophila wing. (C) 2014 The Authors. Published by Elsevier Ltd.
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