期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 22, 期 4, 页码 366-376出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2011.01.001
关键词
Trafficking; Paraspeckles; Localization; Nucleus; Cytoplasm; Neurons; Development
资金
- Australian Research Council/University of Queensland [FF0561986]
- Australian Research Council
Whole genome transcriptomic analyses have identified large numbers of dynamically expressed long non-protein-coding RNAs (lncRNAs) in mammals and other animals whose functions are, as yet, largely unknown. Here we summarize the growing evidence that lncRNAs, like mRNAs, can be trafficked to and function in a wide variety of subcellular locations. Investigation of the subcellular distribution of lncRNAs has the potential to greatly expand our knowledge not only of the function of lncRNAs but also of cell biology by identifying previously unknown subcellular structures and novel constituents of known cellular organelles. (C) 2011 Elsevier Ltd. All rights reserved.
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