期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 21, 期 9, 页码 892-898出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2010.08.004
关键词
Cytokinesis; Contractile ring; Node; Anillin; Myosin
资金
- American Heart Association, Great Rivers Affiliate
- March of Dimes Foundation
- National Institute of Health (NIH) [GM086546]
Most eukaryotes including fungi, amoebas, and animal cells assemble an actin/myosin-based contractile ring during cytokinesis. The majority of proteins implied in ring formation, maturation, and constriction are evolutionarily conserved, suggesting that common mechanisms exist among these divergent eukaryotes. Here, we review the recent advances in positioning and assembly of the actomyosin ring in the fission yeast Schizosaccharomyces pombe, the budding yeast Saccharomyces cerevisiae, and animal cells. In particular, major findings have been made recently in understanding ring formation in genetically tractable S. pombe, revealing a dynamic and robust search, capture, pull, and release mechanism. (C) 2010 Elsevier Ltd. All rights reserved.
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