期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 19, 期 6, 页码 586-595出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2008.07.013
关键词
miRNA; ta-siRNA; Development; Expression pattern; Robustness
资金
- EU integrated project SIRROCO [LSHG-CT-2006-037900]
MicroRNAs (miRNAs) are endogenous small regulatory RNAs, which control gene expression in eukaryotes. In plants they repress mRNA targets containing a highly complementary site, either by cleavage or translational repression. Studies of individual miRNA/target interactions highlight the involvement of the miRNA-based regulations in a broad range of developmental programs, throughout plant lifecycle. MicroRNAs can have distinct regulatory functions on their targets: some determine their spatial accumulation, some have a buffering role that ensures the robustness of their expression pattern, and finally others establish the temporal expression of targeted genes. (c) 2008 Elsevier Ltd. All rights reserved.
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