The one-pot synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives using sulfonic acid functionalized silica (SiO2-Pr-SO3H) under solvent free conditions

An efficient and simple method for the synthesis of biologically active 14-aryl-14H-dibenzo[a,j]xanthenes has been achieved through a one-pot condensation of aryl aldehydes and beta-naphthol under solvent-free conditions in the presence of Sulfonic acid functionalized silica (SiO2-Pr-SO3H), as an efficient heterogeneous solid acid catalyst with excellent yields and short reaction time. (C) 2011 Sharif University of Technology. Production and hosting by Elsevier B.V. All rights reserved.