相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Repurposing pharma assets: an accelerated mechanism for strengthening the schistosomiasis drug development pipeline
Roopa Ramamoorthi et al.
FUTURE MEDICINAL CHEMISTRY (2015)
Flatworms have lost the right open reading frame kinase 3 gene during evolution
Bert Breugelmans et al.
SCIENTIFIC REPORTS (2015)
Application of RNAi to Genomic Drug Target Validation in Schistosomes
Alessandra Guidi et al.
PLOS NEGLECTED TROPICAL DISEASES (2015)
Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni
Gordana Panic et al.
PLOS NEGLECTED TROPICAL DISEASES (2015)
The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease
Janan T. Eppig et al.
NUCLEIC ACIDS RESEARCH (2015)
Trimmomatic: a flexible trimmer for Illumina sequence data
Anthony M. Bolger et al.
BIOINFORMATICS (2014)
InterProScan 5: genome-scale protein function classification
Philip Jones et al.
BIOINFORMATICS (2014)
Polypharmacology: Challenges and Opportunities in Drug Discovery
Andrew Anighoro et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
WormBase 2014: new views of curated biology
Todd W. Harris et al.
NUCLEIC ACIDS RESEARCH (2014)
DrugBank 4.0: shedding new light on drug metabolism
Vivian Law et al.
NUCLEIC ACIDS RESEARCH (2014)
Chemical and Genetic Validation of the Statin Drug Target to Treat the Helminth Disease, Schistosomiasis
Liliana Rojo-Arreola et al.
PLOS ONE (2014)
Imatinib Treatment Causes Substantial Transcriptional Changes in Adult Schistosoma mansoni In Vitro Exhibiting Pleiotropic Effects
Christin Buro et al.
PLOS NEGLECTED TROPICAL DISEASES (2014)
Regulation of Schistosoma mansoni Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway
Luiza Freire de Andrade et al.
PLOS NEGLECTED TROPICAL DISEASES (2014)
Protein Kinase C and Extracellular Signal-Regulated Kinase Regulate Movement, Attachment, Pairing and Egg Release in Schistosoma mansoni
Margarida Ressurreicao et al.
PLOS NEGLECTED TROPICAL DISEASES (2014)
Venus Kinase Receptors Control Reproduction in the Platyhelminth Parasite Schistosoma mansoni
Mathieu Vanderstraete et al.
PLOS PATHOGENS (2014)
Serum albumin and α-1 acid glycoprotein impede the killing of Schistosoma mansoni by the tyrosine kinase inhibitor Imatinib
Svenja Beckmann et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE (2014)
Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis
Marion Morel et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE (2014)
Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs
Steffen Hahnel et al.
FRONTIERS IN GENETICS (2014)
Receptor tyrosine kinases and schistosome reproduction: new targets for chemotherapy
Marion Morel et al.
FRONTIERS IN GENETICS (2014)
Proteomics analysis of differentially expressed proteins in schistosomula and adult worms of Schistosoma japonicum
Yang Hong et al.
ACTA TROPICA (2013)
Time to set the agenda for schistosomiasis elimination
David Rollinson et al.
ACTA TROPICA (2013)
Kinannote, a computer program to identify and classify members of the eukaryotic protein kinase superfamily
Jonathan M. Goldberg et al.
BIOINFORMATICS (2013)
Novel Drosophila model of myotonic dystrophy type 1: phenotypic characterization and genome-wide view of altered gene expression
Lucie Picchio et al.
HUMAN MOLECULAR GENETICS (2013)
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
Kazutaka Katoh et al.
MOLECULAR BIOLOGY AND EVOLUTION (2013)
A public-private partnership to unlock the untargeted kinome
Stefan Knapp et al.
NATURE CHEMICAL BIOLOGY (2013)
Imatinib activity on Schistosoma mansoni
Naftale Katz et al.
MEMORIAS DO INSTITUTO OSWALDO CRUZ (2013)
CDD: conserved domains and protein three-dimensional structure
Aron Marchler-Bauer et al.
NUCLEIC ACIDS RESEARCH (2013)
New approaches for understanding mechanisms of drug resistance in schistosomes
Robert M. Greenberg
PARASITOLOGY (2013)
The Carcinogenic Liver Fluke, Clonorchis sinensis: New Assembly, Reannotation and Analysis of the Genome and Characterization of Tissue Transcriptomes
Yan Huang et al.
PLOS ONE (2013)
Dual Targeting of Insulin and Venus Kinase Receptors of Schistosoma mansoni for Novel Anti-schistosome Therapy
Mathieu Vanderstraete et al.
PLOS NEGLECTED TROPICAL DISEASES (2013)
Functional Mapping of Protein Kinase A Reveals Its Importance in Adult Schistosoma mansoni Motor Activity
Paulu S. R. de Saram et al.
PLOS NEGLECTED TROPICAL DISEASES (2013)
Break Out: Urogenital Schistosomiasis and Schistosoma haematobium Infection in the Post-Genomic Era
Paul J. Brindley et al.
PLOS NEGLECTED TROPICAL DISEASES (2013)
Praziquantel Treatment in Trematode and Cestode Infections: An Update
Jong-Yil Chai
INFECTION AND CHEMOTHERAPY (2013)
Tex14, a Plk1-Regulated Protein, Is Required for Kinetochore-Microtubule Attachment and Regulation of the Spindle Assembly Checkpoint
Gourish Monda et al.
MOLECULAR CELL (2012)
Nearly complete rRNA genes from 371 Animalia: Updated structure-based alignment and detailed phylogenetic analysis
Jon Mallatt et al.
MOLECULAR PHYLOGENETICS AND EVOLUTION (2012)
Whole-genome sequence of Schistosoma haematobium
Neil D. Young et al.
NATURE GENETICS (2012)
Fast gapped-read alignment with Bowtie 2
Ben Langmead et al.
NATURE METHODS (2012)
ChEMBL: a large-scale bioactivity database for drug discovery
Anna Gaulton et al.
NUCLEIC ACIDS RESEARCH (2012)
MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space
Fredrik Ronquist et al.
SYSTEMATIC BIOLOGY (2012)
A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni
Anna V. Protasio et al.
PLOS NEGLECTED TROPICAL DISEASES (2012)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni
Luiza F. Andrade et al.
BMC GENOMICS (2011)
Piggy-backing the concept of cancer drugs for schistosomiasis treatment: a tangible perspective?
Colette Dissous et al.
TRENDS IN PARASITOLOGY (2011)
Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12
N. Badiola et al.
CELL DEATH & DISEASE (2011)
Elucidating the transcriptome of Fasciola hepatica - A key to fundamental and biotechnological discoveries for a neglected parasite
Neil D. Young et al.
BIOTECHNOLOGY ADVANCES (2010)
Conservation of protein kinase a catalytic subunit sequences in the schistosome pathogens of humans
Brett E. Swierczewski et al.
EXPERIMENTAL PARASITOLOGY (2010)
Selectively Nonselective Kinase Inhibition: Striking the Right Balance
Richard Morphy
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Cloning and Characterisation of Schistosoma japonicum Insulin Receptors
Hong You et al.
PLOS ONE (2010)
The Syk Kinase SmTK4 of Schistosoma mansoni Is Involved in the Regulation of Spermatogenesis and Oogenesis
Svenja Beckmann et al.
PLOS PATHOGENS (2010)
The Current Status of Drug Discovery Against the Human Kinome
Richard M. Eglen et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2009)
BLAST plus : architecture and applications
Christiam Camacho et al.
BMC BIOINFORMATICS (2009)
Signal transduction regulates schistosome reproductive biology
Philip T. LoVerde et al.
CURRENT OPINION IN MICROBIOLOGY (2009)
The Schistosoma japonicum genome reveals features of host-parasite interplay
Yan Zhou et al.
NATURE (2009)
The genome of the blood fluke Schistosoma mansoni
Matthew Berriman et al.
NATURE (2009)
Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases
David M. A. Martin et al.
NUCLEIC ACIDS RESEARCH (2009)
Immunopathogenesis of human schistosomiasis
M. L. Burke et al.
PARASITE IMMUNOLOGY (2009)
A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni
Conor R. Caffrey et al.
PLOS ONE (2009)
A wake up call for urinary schistosomiasis: reconciling research effort with public health importance
D. Rollinson
PARASITOLOGY (2009)
A Schistosome cAMP-Dependent Protein Kinase Catalytic Subunit Is Essential for Parasite Viability
Brett E. Swierczewski et al.
PLOS NEGLECTED TROPICAL DISEASES (2009)
Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening
Maha-Hamadien Abdulla et al.
PLOS NEGLECTED TROPICAL DISEASES (2009)
Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis
Michael J. Doenhoff et al.
CURRENT OPINION IN INFECTIOUS DISEASES (2008)
INSULIN RECEPTORS AND GLUCOSE UPTAKE IN THE HUMAN PARASITE SCHISTOSOMA MANSONI
A. Ahier et al.
PARASITE (2008)
Mechanisms of specificity in protein phosphorylation (vol 8, pg 530, 2007)
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Mechanisms of specificity in protein phosphorylation
Jeffrey A. Ubersax et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Association Between Schistosomiasis and Cancer A Review
Emilio Palumbo
INFECTIOUS DISEASES IN CLINICAL PRACTICE (2007)
Structural and functional diversity of the microbial kinome
Natarajan Kannan et al.
PLOS BIOLOGY (2007)
Cell cycle kinases in cancer
Marcos Malumbres et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
The distribution of motor proteins in the muscles and flame cells of the Schistosoma mansoni miracidium and primary sporocyst
D. Bahia et al.
PARASITOLOGY (2006)
TEX14 is essential for intercellular bridges and fertility in male mice
MP Greenbaum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Association between genital schistosomiasis and HIV in rural Zimbabwean women
EF Kjetland et al.
AIDS (2006)
Endoplasmic reticulum stress: cell life and death decisions
CY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Automated generation of heuristics for biological sequence comparison
GS Slater et al.
BMC BIOINFORMATICS (2005)
Conservation of epidermal growth factor receptor function in the human parasitic helminth Schistosoma mansoni
J Vicogne et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
RC Edgar
BMC BIOINFORMATICS (2004)
The Schistosoma mansoni Src kinase TK3 is expressed in the gonads and likely involved in cytoskeletal organization
K Kapp et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2004)
OrthoMCL: Identification of ortholog groups for eukaryotic genomes
L Li et al.
GENOME RESEARCH (2003)
Sequence and expression of testis-expressed gene 14 (Tex14):: a gene encoding a protein kinase preferentially expressed during spermatogenesis
MH Wu et al.
GENE EXPRESSION PATTERNS (2003)
Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa
MJ van der Werf et al.
ACTA TROPICA (2003)
An unusual receptor tyrosine kinase of Schistosoma mansoni contains a Venus Flytrap module
J Vicogne et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Evolution of protein kinase signaling from yeast to man
G Manning et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1α
S Lim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
BLAT - The BLAST-like alignment tool
WJ Kent
GENOME RESEARCH (2002)
Protein kinases - the major drug targets of the twenty-first century?
P Cohen
NATURE REVIEWS DRUG DISCOVERY (2002)
Identification, isolation and characterization of a Fyn-like tyrosine kinase from Schistosoma mansoni
K Kapp et al.
PARASITOLOGY (2001)
The regulation of protein function by multisite phosphorylation - a 25 year update
P Cohen
TRENDS IN BIOCHEMICAL SCIENCES (2000)
KEGG: Kyoto Encyclopedia of Genes and Genomes
M Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2000)