期刊
SCIENCE TRANSLATIONAL MEDICINE
卷 6, 期 245, 页码 -出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.3005975
关键词
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资金
- NIH [R37 GM36477, R01 EB008396, UH2 EB017103, R01 DK85713, RO1 DK48794, R01 DK099320, PO1 DK096990]
- Department of Defense [W81XWH-09-1-0658, W81XWH-11-1-0803]
Despite the tremendous hurdles presented by the complexity of the liver's structure and function, advances in liver physiology, stem cell biology and reprogramming, and the engineering of tissues and devices are accelerating the development of cell-based therapies for treating liver disease and liver failure. This State of the Art Review discusses both the near- and long-term prospects for such cell-based therapies and the unique challenges for clinical translation.
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