期刊
SCIENCE TRANSLATIONAL MEDICINE
卷 4, 期 165, 页码 -出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.3004404
关键词
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资金
- Wellcome Trust
- Medical Research Council (UK)
- Biotechnology and Biological Sciences Research Council (BBSRC)
- U.S. National Institute for Allergy and Infectious Diseases
- Fungal Research Trust
- European Union [HEALTH-2010-260338]
- National Institute for Health Research
- National Health Service National Commissioning Group
- European Commission (Ariadne, ALLFUN)
- NIH [RO1AI025780, R21AI093302, AI081235, DE11367, DE14161, DE017078]
- Netherlands Organization for Scientific Research
- Gilead Sciences
- MRC [MR/J004820/1] Funding Source: UKRI
- Medical Research Council [MR/J004820/1] Funding Source: researchfish
Although fungal infections contribute substantially to human morbidity and mortality, the impact of these diseases on human health is not widely appreciated. Moreover, despite the urgent need for efficient diagnostic tests and safe and effective new drugs and vaccines, research into the pathophysiology of human fungal infections lags behind that of diseases caused by other pathogens. In this Review, we highlight the importance of fungi as human pathogens and discuss the challenges we face in combating the devastating invasive infections caused by these microorganisms, in particular in immunocompromised individuals.
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