4.8 Article

Temsirolimus Activates Autophagy and Ameliorates Cardiomyopathy Caused by Lamin A/C Gene Mutation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cardiac & Cardiovascular Systems

Haploinsufficiency of Target of Rapamycin Attenuates Cardiomyopathies in Adult Zebrafish

Yonghe Ding et al.

CIRCULATION RESEARCH (2011)

Article Cell Biology

LMNA cardiomyopathy: cell biology and genetics meet clinical medicine

Jonathan T. Lu et al.

DISEASE MODELS & MECHANISMS (2011)

Article Medicine, Research & Experimental

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation

Talita M. Marin et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Cell Biology

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Cell Biology

Inhibition of autophagy in the heart induces age-related cardiomyopathy

Manabu Taneike et al.

AUTOPHAGY (2010)

Article Biochemistry & Molecular Biology

Methods in Mammalian Autophagy Research

Noboru Mizushima et al.

Article Cell Biology

Mammalian autophagy: core molecular machinery and signaling regulation

Zhifen Yang et al.

CURRENT OPINION IN CELL BIOLOGY (2010)

Article Medicine, Research & Experimental

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

Denghong Zhang et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Review Biochemistry & Molecular Biology

Autophagy and the Integrated Stress Response

Guido Kroemer et al.

MOLECULAR CELL (2010)

Article Biochemistry & Molecular Biology

A complex interplay between Akt, TSC2 and the two mTOR complexes

Jingxiang Huang et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2009)

Review Cell Biology

The Nuclear Envelope as a Signaling Node in Development and Disease

William T. Dauer et al.

DEVELOPMENTAL CELL (2009)

Review Biochemistry & Molecular Biology

Autophagy in the pathogenesis of disease

Beth Levine et al.

Article Multidisciplinary Sciences

Autophagy is an adaptive response in desmin-related cardiomyopathy

Paul Tannous et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Cell Biology

FoxO3 controls autophagy in skeletal muscle in vivo

Cristina Mammucari et al.

CELL METABOLISM (2007)

Article Biochemistry & Molecular Biology

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

Serhiy Pankiv et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Endocrinology & Metabolism

Rapamycin prevents thyroid hormone-induced cardiac hypertrophy

James A. Kuzman et al.

ENDOCRINOLOGY (2007)

Article Biochemistry & Molecular Biology

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Atsuko Nakai et al.

NATURE MEDICINE (2007)

Article Medicine, Research & Experimental

Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy

Antoine Muchir et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Biochemistry & Molecular Biology

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

Yasemin Sancak et al.

MOLECULAR CELL (2007)

Article Cell Biology

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Emilie Vander Haar et al.

NATURE CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

DD Sarbassov et al.

MOLECULAR CELL (2006)

Article Cardiac & Cardiovascular Systems

Propranolol prevents enhanced stress signaling in Gsα cardiomyopathy:: potential mechanism for β-blockade in heart failure

V Karoor et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Rapamycin attenuates load-induced cardiac hypertrophy in mice

T Shioi et al.

CIRCULATION (2003)

Article Cell Biology

Akt regulates growth by directly phosphorylating Tsc2

CJ Potter et al.

NATURE CELL BIOLOGY (2002)

Article Cell Biology

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

K Inoki et al.

NATURE CELL BIOLOGY (2002)