期刊
SCIENCE SIGNALING
卷 2, 期 67, 页码 -出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scisignal.267pe24
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资金
- NCI NIH HHS [K99 CA129613-01A1, K99 CA129613-02, K99 CA129613] Funding Source: Medline
- NIGMS NIH HHS [R01 GM072555, R01 GM072555-04] Funding Source: Medline
A flurry of reports indicates that we are entering a new phase in the development of mammalian target of rapamycin (mTOR)-based therapies for oncology. Here, we summarize exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to study the mTOR pathway and as drugs in the clinic.
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