期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 437, 期 -, 页码 185-195出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2012.08.021
关键词
Selective serotonin re-uptake inhibitors; Ecopharmacovigilance; Sources; Fate; Occurrence; Aquatic environment
资金
- Fundacao para a Ciencia e a Tecnologia (FCT)
- FEDER/POCTI
- FCT [SFRH/BPD/62877/2009]
Selective serotonin re-uptake inhibitors (SSRIs) antidepressants are among the most prescribed pharmaceutical active substances throughout the world. The occurrence of these widely used compounds in different environmental compartments (wastewaters, surface, ground and drinking waters, and sediments), justify the growing concern about these emerging environmental pollutants. Viewing an ecopharmacovigilance approach, a comprehensive discussion of the state of the art regarding different contamination sources, fate, degradation and occurrence is presented. Information on the current distribution levels and fate in different environmental matrices continues to be sparse and measures are imperative to improve awareness and encourage precautionary actions to minimize SSRIs' environmental impact. (C) 2012 Elsevier B.V. All rights reserved.
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