A unique polymeric gel by thiol-alkyne click chemistry

Poly(ethylene glycol) functionalized with tetra-acetylene (PTETACT) and pentaerythritol (3-mercaptopropionic acid) (PETM) are cross-linked by a thiol-yne reaction to create robust, tuneable networks. A new class of unique gels is produced by gelations in various organic solvents as well as water. This is the first report of creating 3D gel networks by a thiol-alkyne reaction in the presence of triethylamine under moderate temperature.