4.7 Review

Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Mutagenesis Mapping of the Presenilin 1 Calcium Leak Conductance Pore

Omar Nelson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Medicine, Research & Experimental

Correlating familial Alzheimer's disease gene mutations with clinical phenotype

Natalie S. Ryan et al.

BIOMARKERS IN MEDICINE (2010)

Review Cell Biology

The dysregulation of intracellular calcium in Alzheimer disease

Charlene Supnet et al.

CELL CALCIUM (2010)

Article Neurosciences

Neuronal Calcium Signaling, Mitochondrial Dysfunction, and Alzheimer's Disease

Charlene Supnet et al.

JOURNAL OF ALZHEIMERS DISEASE (2010)

Article Biochemistry & Molecular Biology

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

Angelo Demuro et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Neurosciences

Role of Presenilins in Neuronal Calcium Homeostasis

Hua Zhang et al.

JOURNAL OF NEUROSCIENCE (2010)

Review Clinical Neurology

γ-secretases: from cell biology to therapeutic strategies

Bruno A. Bergmans et al.

LANCET NEUROLOGY (2010)

Article Multidisciplinary Sciences

Structural investigation of the C-terminal catalytic fragment of presenilin 1

Solmaz Sobhanifar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Clinical Neurology

Variations in the neuropathology of familial Alzheimer's disease

Claire Shepherd et al.

ACTA NEUROPATHOLOGICA (2009)

Review Biochemistry & Molecular Biology

The amyloid hypothesis for Alzheimer's disease: a critical reappraisal

John Hardy

JOURNAL OF NEUROCHEMISTRY (2009)

Review Cell Biology

Presenilin: RIP and beyond

Matthew R. Hass et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)

Review Biochemistry & Molecular Biology

Calcium signaling and neurodegenerative diseases

Ilya Bezprozvanny

TRENDS IN MOLECULAR MEDICINE (2009)

Article Biochemistry & Molecular Biology

Transmembrane domain 9 of presenilin determines the dynamic conformation of the catalytic site of γ-secretase

Alexandra Tolia et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Review Neurosciences

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

Lars Bertram et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Review Genetics & Heredity

Loss of progranulin function in frontotemporal lobar degeneration

Marc Cruts et al.

TRENDS IN GENETICS (2008)

Review Neurosciences

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

Ilya Bezprozvanny et al.

TRENDS IN NEUROSCIENCES (2008)

Review Clinical Neurology

The pathogenesis of alzheimers disease - Is it a lifelong Calciumopathy?

Grace E. Stutzmann

NEUROSCIENTIST (2007)

Article Clinical Neurology

Forecasting the global burden of Alzheimer's disease

Ron Brookmeyer et al.

ALZHEIMERS & DEMENTIA (2007)

Article Medicine, Research & Experimental

Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1

Omar Nelson et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Biochemistry & Molecular Biology

Contribution of presenilin transmembrane domains 6 and 7 to a water-containing cavity in the γ-secretase complex

Alexandra Tolia et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway

Dragana Spasic et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Electron microscopic structure of purified, active γ-secretase reveals an aqueous intramembrane chamber and two pores

VK Lazarov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Detection of presenilin-1 homodimer formation in intact cells using fluorescent lifetime imaging microscopy

L Herl et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Biochemistry & Molecular Biology

A nine-transmembrane domain topology for presenilin 1

H Laudon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease

IF Smith et al.

JOURNAL OF NEUROCHEMISTRY (2005)

Article Clinical Neurology

Pick bodies in a family with presenilin-1 Alzheimer's disease

GM Halliday et al.

ANNALS OF NEUROLOGY (2005)

Article Biochemistry & Molecular Biology

Presenilin regulates capacitative calcium entry dependently and independently of γ-secretase activity

Y Akbari et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Multidisciplinary Sciences

γ-secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

WT Kimberly et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Cell Biology

Reconstitution of γ-secretase activity

D Edbauer et al.

NATURE CELL BIOLOGY (2003)

Article Multidisciplinary Sciences

The role of presenilin cofactors in the γ-secretase complex

N Takasugi et al.

NATURE (2003)

Article Biochemistry & Molecular Biology

Dimerization of presenilin-1 in vivo:: suggestion of novel regulatory mechanisms leading to higher order complexes

SS Hébert et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Review Neurosciences

Alzheimer's disease with spastic paresis and cotton wool type plaques

T Tabira et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2002)

Article Clinical Neurology

Variant Alzheimer disease with spastic paraparesis: Neuropathological phenotype

A Verkkoniemi et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)

Article Biochemistry & Molecular Biology

Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons

SL Chan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)