期刊
SCIENCE CHINA-CHEMISTRY
卷 56, 期 12, 页码 1682-1692出版社
SCIENCE PRESS
DOI: 10.1007/s11426-013-5004-8
关键词
molecular imaging; positron emission tomography; F-18-fluorine/fluoride; specific activity; radiochemical yield
资金
- National Natural Science Foundation of China [11304156]
- General Financial Grant from the China Postdoctoral Science Foundation [2013M531312]
Much research effort has been made to understand various biological processes at levels of molecules using molecular imaging techniques. Because of great sensitivity, high resolution, and rapid detection, positron emission tomography (PET) imaging is becoming one of the most used imaging techniques for medical diagnose and pre-clinical studies. Here we provide a review on molecular imaging and PET imaging. An introduction is also provided on F-18-fluorine labeling techniques for the preparation of PET imaging probes. A summary and comparison of currently available F-18-fluorine labeling methods is provided. The perspectives for F-18-fluorine labeling techniques are also given.
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