期刊
RSC ADVANCES
卷 5, 期 30, 页码 23646-23649出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra17072e
关键词
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资金
- National Natural Science Foundation of China [21174022, 21376038, 21421005]
- National Basic Research Program of China [2013CB733702]
- Program for Changjiang Scholars and Innovative Research Team in University [IRT1213]
- Fundamental Research Funds for the Central Universities [DUT14YQ103]
- Specialized Research Fund for the Doctoral Program of Higher Education [20110041110009]
We have developed a terminal alkyne substituted O6-benzylguanine, named PYBG, as a versatile precursor to be facilely conjugated with various fluorescent dyes through 'Click chemistry' and Sonogashira coupling reactions. These fluorescent PYBG derivatives specifically and efficiently label the target genetically encoded SNAP-tags in live cells.
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