期刊
SCIENCE
卷 345, 期 6194, 页码 -出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1249721
关键词
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资金
- French National Research Agency [ANR-09-GENM-025 3BSEQ]
- France Agrimer
- INRA BAP Biologie et Amelioration des Plantes division
- European Commission research training program Marie-Curie Actions (FP7-MC-IIF-NoncollinearGenes)
- French Ministry of Research
- Region Auvergne
- Ghent University Multidisciplinary Research Partnership [Bioinformatics: From nucleotides to networks] [01MR0310W]
- Czech Science Foundation [P501/12/G090]
- Biotechnology and Biological Sciences Research Council [BBS/E/T/000PR6193] Funding Source: researchfish
- BBSRC [BBS/E/T/000PR6193] Funding Source: UKRI
We produced a reference sequence of the 1-gigabase chromosome 3B of hexaploid bread wheat. By sequencing 8452 bacterial artificial chromosomes in pools, we assembled a sequence of 774 megabases carrying 5326 protein-coding genes, 1938 pseudogenes, and 85% of transposable elements. The distribution of structural and functional features along the chromosome revealed partitioning correlated with meiotic recombination. Comparative analyses indicated high wheat-specific inter-and intrachromosomal gene duplication activities that are potential sources of variability for adaption. In addition to providing a better understanding of the organization, function, and evolution of a large and polyploid genome, the availability of a high-quality sequence anchored to genetic maps will accelerate the identification of genes underlying important agronomic traits.
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