A novel pyrazoline-based fluorescent probe for detecting fluoride ion in water and its application on real samples

We have designed and synthesized a new fluorescent probe, 2-(3-(2-((tert-butyldiphenylsilyl) oxy) phenyl)5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzo[d]thiazole (probe 1), to detect fluoride ion with high selectivity and sensitivity in aqueous media. Upon mixing with NaF, desilylation reaction of probe 1 can be induced to the fluorescence quenching with the detection limit of F- 0.74 mu M. Moreover, the probe can be used to detect fluoride ion on real life samples.