期刊
SCIENCE
卷 337, 期 6095, 页码 735-737出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1223154
关键词
-
资金
- NIH [NS34994, MH54671, NS074015]
- Human Frontier Science Program
- J. D. McDonnell Foundation
- European Community [254780]
- Rosztoczy Foundation
Many neurological and psychiatric diseases are associated with clinically detectable, altered brain dynamics. The aberrant brain activity, in principle, can be restored through electrical stimulation. In epilepsies, abnormal patterns emerge intermittently, and therefore, a closed-loop feedback brain control that leaves other aspects of brain functions unaffected is desirable. Here, we demonstrate that seizure-triggered, feedback transcranial electrical stimulation (TES) can dramatically reduce spike-and-wave episodes in a rodent model of generalized epilepsy. Closed-loop TES can be an effective clinical tool to reduce pathological brain patterns in drug-resistant patients.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据