期刊
SCIENCE
卷 338, 期 6108, 页码 822-824出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1225720
关键词
-
资金
- Sandler Postdoctoral Fellowship
- Herbert Boyer Junior Faculty Endowed Chair Award
- NIH [R01GM097017, R01GM070808, R01GM026259, P50Gm081879, 5RO1GM097213-02]
- NIH National Research Service Award fellowship
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [05/00587-5, 07/50882-9]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [301303/06-1]
- Packard Fellowship
- China Scholarship Council (CSC) scholarship
- Boyer Postdoctoral Fellowship
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [07/50882-9, 05/00587-5] Funding Source: FAPESP
Mitochondria must grow with the growing cell to ensure proper cellular physiology and inheritance upon division. We measured the physical size of mitochondrial networks in budding yeast and found that mitochondrial network size increased with increasing cell size and that this scaling relation occurred primarily in the bud. The mitochondria-to-cell size ratio continually decreased in aging mothers over successive generations. However, regardless of the mother's age or mitochondrial content, all buds attained the same average ratio. Thus, yeast populations achieve a stable scaling relation between mitochondrial content and cell size despite asymmetry in inheritance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据