期刊
SCIENCE
卷 334, 期 6052, 页码 94-98出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1211177
关键词
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资金
- Biotechnology and Biological Sciences Research Council [BB/H008802/2, BB/H008802/1, BB/H005854/1] Funding Source: researchfish
- Novo Nordisk Fonden [NNF10CC1016517] Funding Source: researchfish
- BBSRC [BB/H005854/1, BB/H008802/2, BB/H008802/1] Funding Source: UKRI
- Grants-in-Aid for Scientific Research [21405014] Funding Source: KAKEN
- Biotechnology and Biological Sciences Research Council [BB/H008802/1, BB/H005854/1] Funding Source: Medline
- NHGRI NIH HHS [R01 HG003229] Funding Source: Medline
We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.
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