期刊
SCIENCE
卷 328, 期 5986, 页码 1668-1673出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1190470
关键词
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资金
- NSF [DMR-0964886]
- Air Force Office of Scientific Research [FA9550-07-1-0484]
- Gordon and Betty Moore Foundation at Caltech
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [964886] Funding Source: National Science Foundation
Electron tomography provides three-dimensional (3D) imaging of noncrystalline and crystalline equilibrium structures, as well as elemental volume composition, of materials and biological specimens, including those of viruses and cells. We report the development of 4D electron tomography by integrating the fourth dimension (time resolution) with the 3D spatial resolution obtained from a complete tilt series of 2D projections of an object. The different time frames of tomograms constitute a movie of the object in motion, thus enabling studies of nonequilibrium structures and transient processes. The method was demonstrated using carbon nanotubes of a bracelet-like ring structure for which 4D tomograms display different modes of motion, such as breathing and wiggling, with resonance frequencies up to 30 megahertz. Applications can now make use of the full space-time range with the nanometer-femtosecond resolution of ultrafast electron tomography.
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