期刊
SCIENCE
卷 324, 期 5927, 页码 646-648出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1168450
关键词
-
资金
- Moore Foundation
- Economic Research Service of the U.S. Department of Agriculture on Behavioral Health Economics Research on Dietary Choice and Obesity
Every day, individuals make dozens of choices between an alternative with higher overall value and a more tempting but ultimately inferior option. Optimal decision-making requires self-control. We propose two hypotheses about the neurobiology of self-control: (i) Goal-directed decisions have their basis in a common value signal encoded in ventromedial prefrontal cortex (vmPFC), and (ii) exercising self-control involves the modulation of this value signal by dorsolateral prefrontal cortex (DLPFC). We used functional magnetic resonance imaging to monitor brain activity while dieters engaged in real decisions about food consumption. Activity in vmPFC was correlated with goal values regardless of the amount of self-control. It incorporated both taste and health in self-controllers but only taste in non-self-controllers. Activity in DLPFC increased when subjects exercised self-control and correlated with activity in vmPFC.
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