Supermolecular self assembly of AIE-active nanoprobes: fabrication and bioimaging applications

Luminescent polymeric nanoparticles (LPNs) have attracted great attention in the field of biosensors, bioimaging and therapy. In this work, we reported that novel aggregation induced emission dye based LPNs can be facilely and efficiently fabricated through supermolecular self assembly. TPE-Ad/beta-CD LPNs possess strong luminescent intensity, uniform size, high water dispersibility and desirable biocompatibility, making them promising candidates for bioimaging applications.