期刊
SCIENCE
卷 322, 期 5909, 页码 1865-1868出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1166466
关键词
-
资金
- Kavli Foundation
- Norwegian Research Council
- European Commission Framework 7 project (SPACEBRAIN)
We report the existence of an entorhinal cell type that fires when an animal is close to the borders of the proximal environment. The orientation- specific edge- apposing activity of these border cells is maintained when the environment is stretched and during testing in enclosures of different size and shape in different rooms. Border cells are relatively sparse, making up less than 10% of the local cell population, but can be found in all layers of the medial entorhinal cortex as well as the adjacent parasubiculum, often intermingled with head- direction cells and grid cells. Border cells may be instrumental in planning trajectories and anchoring grid fields and place fields to a geometric reference frame.
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