期刊
SCIENCE
卷 322, 期 5906, 页码 1384-1387出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1164216
关键词
-
资金
- NIH [GM069462]
- University of Arizona NSF- IGERT ( Integrative Graduate Education and Research Traineeships) Program in Genomics
- Graduate Training in Biochemistry and Molecular Biology
Polytene chromosome structure is a characteristic of some polyploid cells where several to thousands of chromatids are closely associated with perfect alignment of homologous DNA sequences. Here, we show that Drosophila condensin II promotes disassembly of polytene structure into chromosomal components. Condensin II also negatively regulates transvection, a process whereby certain alleles are influenced transcriptionally via interallelic physical associations. We propose that condensin II restricts trans- chromosomal interactions that affect transcription through its ability to spatially separate aligned interphase chromosomes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据