期刊
RSC ADVANCES
卷 5, 期 110, 页码 90457-90465出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra18333b
关键词
-
资金
- Shandong Province Natural Science Foundation [ZR2014FQ032]
- Taishan Scholars Program of Shandong province
- National Natural Science Foundation of China [61205174]
An efficient surface enhanced Raman scattering (SERS) substrate of graphene-isolated Ag nanoparticle (G/AgNP) has been developed by using excimer laser to ablate the ordered pyrolytic graphite in high vacuum onto Ag nanoparticles. By combining the electromagnetic activity of AgNPs and unique physical/chemical properties of graphene, the G/AgNP substrates shows high performance in terms of sensitivity, signal-to-noise ratio and reproducibility. The average enhancement factor obtained from the G/AgNP substrates for rhodamine 6G probe molecules is over 10(8). The maximum deviations of SERS intensities from 20 positions of a same SERS substrate are in the range of 4.20% to 6.75% and from 20 different substrates in various batches are in the range of 4.43% to 7.71%, depending on different vibration modes. As a practical application of this SERS system, we detect the adenosine concentration in human serum. The detection results show a good linear correlation between SERS intensity and adenosine concentration within the range of 2 to 200 nM. This work may open up new opportunities in developing the applications of SERS in biomedical diagnostics, biological sensing and other biotechnology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据