A novel and efficient method for the synthesis of 4-substituted 3,5-dinitro-1,4-dihydropyridines by a reaction of beta-formyl-beta-nitroenamines with aldehydes was developed. The reaction of nitroenamines with aldehydes leading to 1,4-dihydropyridines and the self-condensation of nitroenamines leading to pyridinium salt intermediate proceed competitively. The obtained 3,4,5-trisubstituted-1,4-dihydropyridines readily transformed into the corresponding pyridines in high yields.
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