期刊
SCHIZOPHRENIA RESEARCH
卷 146, 期 1-3, 页码 289-290出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.schres.2013.02.021
关键词
Schizophrenia; Bipolar disorder; Monozygotic twin; Discordant; Genetics; Copy number variation; Structural variation
类别
资金
- NARSAD Distinguished Investigator award (Sullivan)
- NIMH [MH052857]
Copy number variation plays a clear role in the etiology of many psychiatric disorders, particularly schizophrenia. We performed array-CGH to look for copy number variants between five pairs of monozygotic twins discordant for bipolar disorder or schizophrenia. Our study found no differences in copy number variants between the sets of twins. Although alluring, realistic accounting for heterogeneity and chimerism highlights the technological limitations in studying monozygotic twins discordant for psychiatric disorders. (C) 2013 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据