期刊
SCHIZOPHRENIA RESEARCH
卷 139, 期 1-3, 页码 211-217出版社
ELSEVIER
DOI: 10.1016/j.schres.2012.05.024
关键词
Schizophrenia; Treatment satisfaction; Patient-related outcome; Second-generation antipsychotics; Psychosocial therapy
类别
资金
- Brystol-Myers Squibb
- Otsuka Pharmaceuticals France
- Eli Lilly
- Janssen-Cilag
- Lundbeck
- Biocodex
- Sanofi-Aventis
- Servier
Background: Knowing the determinants of treatment satisfaction can provide better understanding of patient expectations in schizophrenia. The aim of this study was to determine which treatment-related factors were associated with treatment satisfaction, independently of patient-related or illness-related factors, in schizophrenia patients. Methods: A cross-sectional study of data collected nationwide in France between 2005 and 2006 was conducted. 5500 adult patients with non-acute schizophrenia and requiring a switch of antipsychotic drug were included by 995 psychiatrists. Treatment satisfaction was assessed using the PAtient SAtisfaction with Psychotropics (PASAP) self-report questionnaire. Linear mixed model was used to explore the association between treatment satisfaction and treatment-related factors-including the current antipsychotic drug (none, first or second-generation antipsychotic) and psychosocial therapy-independently of patient-related and illness-related factors. Findings: 3630 (66%) patients filled in the PASAP questionnaire. Main treatment-related determinants of higher levels of satisfaction were: (1) being on second-generation antipsychotics compared to first-generation antipsychotics (olanzapine: beta=1.2; CI95%=[0.5; 2.0], risperidone: beta=0.9; CI95%=[0.1; 1.6], clozapine: beta=2.5; CI95%=[0.6; 4.3] and amisulpride: beta=1.2; CI95%=[0.3; 2.1]) and (2) participating in psychosocial therapy (beta=0.9; CI95%=[0.3; 1.5]). Conclusion: Treatment satisfaction in non-acute schizophrenia was related to the more recent antipsychotic agents and psychosocial therapy, which may reflect expectations of more pro-active care. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据