期刊
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
卷 25, 期 3, 页码 390-397出版社
WILEY
DOI: 10.1111/sms.12240
关键词
Osteoporosis; osteogenesis; tail suspension; exercise therapy; bone tissue; osteoblasts; osteoclasts
资金
- State of Sao Paulo Research Foundation (FAPESP)
- Coordination for the Improvement of Higher Education Personnel (CAPES)
We assessed and compared the effects of swimming, jumping, and vibration therapies on the prevention of bone loss because of unloading. Eighty Wistar rats were randomly divided into eight groups: S, permanent hind limb-suspended rats; CON, control rats; S+Swim, unloading interrupted by swimming exercise; S+C-Swim, suspension interrupted by regular weight-bearing with the same duration as in the S+Swim protocol; S+Jump, unloading interrupted by jumping exercise; S+C-Jump, suspension interrupted for regular weight-bearing as in the S+Jump group; S+Vibr, unloading interrupted by vibration; and S+C-Vibr, suspension with interruptions for regular weight-bearing with the same protocol as that used for the S+Vibr rats. At the end of the experiment, the bone mineral density, bone strength, histomorphometric parameters, and serum levels of the bone markers were analyzed. The hind limb-suspended rats exhibited bone quality loss. In contrast, the trained rats showed a significant increase in bone mass, bone strength, bone formation, and serum levels of bone markers compared with the respective controls. Although we did not find a significant difference among the three physical exercises, the osteogenic effect of vibration was slightly lower than that of swimming and jumping. Thus, all physical exercises were efficient in preventing bone loss because of unloading and preserving bone quality.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据