期刊
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
卷 22, 期 5, 页码 e108-e114出版社
WILEY
DOI: 10.1111/j.1600-0838.2012.01516.x
关键词
hydroxyproline; hydroxylyslpyridinoline; ovariectomized; exercise; phytoestrogen
资金
- Midwestern University Kenneth A. Suarez Summer Research Fellowship
- College of Health Sciences, Midwestern University Intramural Awards
- NIH [1R15DK071625-01A2]
The objective of this study was to evaluate the effects of genistein and moderate intensity exercise on Achilles tendon collagen and cross-linking in intact and ovariectomized (OVX) female SpragueDawley rats. Rats were separated into eight groups (n?=?9/group): intact or OVX, treadmill exercised or sedentary, genistein-treated (300?mg/kg/day) or vehicle. After 6 weeks, tendons were assayed for the collagen-specific amino acid hydroxyproline and hydroxylyslpyridinoline (HP). Collagen content was not influenced by exercise (P?=?0.40) but was lower (P?
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