期刊
RSC ADVANCES
卷 5, 期 49, 页码 39612-39619出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra06065f
关键词
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资金
- Natural Science Foundation of Anhui Province [1508085QB39]
- National Natural Science Foundation of China [51402001]
- Open Project of State Key Laboratory of Physical Chemistry of Solid Surfaces (Xiamen University) [201416]
- Grants for Scientific Research of BSKY from Anhui Medical University [0115027101]
- Program for the Outstanding Young and Middle-aged Talents of Anhui Medical University [0115027102]
A novel Cu-Ag bimetal antibacterial system is reported. In this Cu-Ag bimetal system, copper silicate nanotubes (CSNTs) and copper silicate nanotube-assembled hollow nanospheres (CSNAHSs) with high BET surface area, unique hollow structure and strong antibacterial activity, were adopted as a carrier for loading silver ions to fabricate the copper-silver bimetal antibacterial agents (designated as Ag+/CSNTs and Ag+/CSNAHSs). Additionally, the antibacterial activity of Ag+/CSNTs and Ag+/CSNAHSs was investigated against Gram-negative bacteria (Escherichia coli BL21 and Escherichia coli JM109) and Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis). The results demonstrated that both silver-loaded copper silicates were highly effective against the four types of bacterial strains, and the Ag+/CSNAHSs showed a stronger antibacterial ability than Ag+/CSNTs due to their more silver loading contents. More importantly, a synergistic effect of copper ions and silver ions on the inhibition of the bacterial growth was observed in our bimetal antibacterial system.
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