Dengue and liver disease

Acute hepatitis and hepatic encephalopathy are rare manifestations of dengue haemorrhagic fever (DHF). We report 4 children aged 8 months to 3 y who presented with severe hepatic dysfunction. Three male infants had in addition hepatic encephalopathy and 2 of them succumbed to their disease suggesting that hepatitis with encephalopathy has a very high mortality.