期刊
RSC ADVANCES
卷 5, 期 41, 页码 32835-32838出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra04632g
关键词
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资金
- Chinese Academy of Sciences
- National Natural Science Foundation of China [21133011, 21373246]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDA09030104]
A direct and eco-friendly nitration methodology to synthesize 3-nitroquinoline N-oxides from quinoline N-oxides using tert-butyl nitrite as both the nitro source and oxidant has been developed. Although this reaction undergoes a free radical process, it exhibits high regioselectivity and can be smoothly scaled up to gram scale.
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