期刊
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
卷 45, 期 6, 页码 684-689出版社
INFORMA HEALTHCARE
DOI: 10.3109/00365521003663662
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Objective. Recent evidence suggests the involvement of the upper gastrointestinal tract in ulcerative colitis (UC). By conducting a prospective controlled study, we explored the immunological abnormalities in the duodenal mucosa of UC patients. Methods. Duodenal and colonic biopsies were collected from 24 corticosteroid-free UC patients and 21 controls. Colonization by Helicobacter pylori and positivity for anti-endomysial antibodies was an exclusion criteria. The severity of duodenal and colonic inflammation was determined by endoscopic and histologic scores. Morphometry was performed to measure the surface area to volume ratio (SV). Duodenal CD3
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