期刊
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
卷 44, 期 10, 页码 1198-1206出版社
TAYLOR & FRANCIS AS
DOI: 10.1080/00365520903132013
关键词
BMI; body mass index; coeliac; gluten intolerance; obesity; overweight; weight; underweight
资金
- Swedish Society of Medicine
- Swedish Research Council
- Karolinska Institutet
- Majblomman Foundation
- Juhlin Foundation
- Clas Groschinsky Foundation
- Swedish Coeliac Society
- Orebro University Hospital
Objective. To examine the relationship between body mass index (BMI) and an inpatient diagnosis of coeliac disease (CD) in two independent Swedish national registers. Material and methods. Study 1: Cohort study of women. The relationship between (pre-pregnancy) BMI and CD in pregnant women was evaluated (174 undiagnosed CD (at time of pregnancy), 550 diagnosed CD, 787,986 without a diagnosis of CD). The association between BMI and undiagnosed CD was estimated by Cox regression. Study 2: Case-control study of men. The relationship between BMI and CD in male conscripts was evaluated (70 undiagnosed CD, 1,047 diagnosed CD and 6,887 without a diagnosis of CD). The association between BMI and undiagnosed CD was estimated by logistic regression. Prevalence of underweight, normal weight and overweight was compared between diagnosed CD, undiagnosed CD and no diagnosis of CD. Results. The prevalence of underweight (BMI<18.5) in women was: reference individual: 5.2%; undiagnosed CD: 16.7% and prior diagnosis of CD: 6.4%. In men, the corresponding figures were 6.5%; 14.3% and 9.8%, respectively. Underweight was associated with undiagnosed CD (future diagnosis of CD) in both women (hazard ration (HR) = 2.5; 95% CI = 1.6-3.7) and men (odds ratio (OR) = 2.4; 95% CI = 1.2-4.9). In women, overweight was negatively associated with undiagnosed CD (HR = 0.6; 95% CI = 0.4-0.9), but not in men (OR = 1.1; 95% CI = 0.6-2.2). 9.2% of women with undiagnosed CD and 14.3% of men with undiagnosed CD were overweight. Conclusions. Underweight individuals are at increased risk of having undiagnosed CD. However, overweight does not rule out CD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据