Ultrasensitive electrochemical assay of hydrogen peroxide and glucose based on PtNi alloy decorated MWCNTs

A novel electrochemical assay based on PtNi/MWCNT nanocomposites was designed for ultrasensitive detection of hydrogen peroxide and glucose. The PtNi/MWCNT nanocomposites have been synthesized by a chemical reduction method and were investigated by X-ray diffraction, transmission electron microscopy, and electrochemical testing. The results demonstrated that the PtNi/MWCNT nanocomposites exhibited excellent electrocatalytic activity toward hydrogen peroxide and glucose. The electrocatalytic reduction of hydrogen peroxide showed a wide linear range from 0.2 mu M to 24.6 mM, with a high sensitivity of 2123.1 mu A mM(-1) cm(-2) and a detection limit of 60 nM (S/N = 3). At the same time, amperometric sensing of glucose was realized in a linear range from 0.1 mu M to 9.0 mM, with an excellent sensitivity of 85 910.0 mu A mM(-1) cm(-2). The present hybrid system also exhibited a good performance in terms of long-time stability, reproducibility and anti-interference ability.