期刊
RSC ADVANCES
卷 5, 期 99, 页码 81162-81167出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra17442b
关键词
-
资金
- Department of Science and Technology, New Delhi [EMR/2014/000873]
- CSIR, New Delhi
The synthesis of the proline-serine core of kaitocephalin 1 was accomplished starting from D-glucose wherein, C2 of D-glucose provided the carboxylic acid functionality of serine; while the amino- and beta-hydroxy groups of the serine fragment were amenable from the C3 and C4 hydroxy groups of sugar. The key intermediate to construct substituted proline with the appropriate quaternary carbon framework of the target molecule was constructed using the Jocic-Reeve and Corey-Link reaction sequence with the desired stereochemistry from the C5-centre of D-glucose.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据