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Tetrazoles: LIII. Microwave-Activated Acylation of 5-Substituted Tetrazoles

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RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
卷 44, 期 9, 页码 1345-1347

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MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1070428008090169

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  1. Russian Foundation for Basic Research [08-03-00342a]

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The acylation of 5-aryl(hetaryl)tetrazoles with acetic and benzoic anhydrides under microwave irradiation gave the corresponding 2-substituted 5-methyl-and 5-phenyl-1,3,4-oxadiazoles in high yields. The use of microwave activation reduces the reaction temperature by 30-40C and shortens the reaction time by a factor of 5 to 7.

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