期刊
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
卷 78, 期 2, 页码 305-312出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1070363208020217
关键词
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Reactions of the polyene macrolide antibiotic pimaricin with aromatic aldehydes and hypophosphorous acid are shown to afford pimaricin hydrophosphoryl derivatives. Physicochemical and biological properties of these compounds are explored. Biological studies indicated that the pimaricin hydrophosphoryl derivatives are low toxic agents possessing a high antifungal activity.
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