4.0 Article

Synthesis of a-secomethylenamino- and substituted amidoximotriterpenoids

期刊

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
卷 37, 期 5, 页码 619-625

出版社

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1068162011050086

关键词

triterpenoids; betulin; ketoximes; cyanoethylation; antiviral; antitubercular activity

资金

  1. Russian Foundation for Basic Research [08-03-00868]

向作者/读者索取更多资源

Development of the functionalization of triterpenoids to A-secoamidoximes, A-secomethylenamines, and branched 3-(3-aminopropylamino)-3-(3-aminopropoxy)amidoximes is illustrated by the betulonic acid ketoxime. An effective way to get of the derivatives of 20,29-dihydrolupanes using diborane is suggested. The antiviral and antituberculosis activity data of some compounds are presented.

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