Dual T1/T2 MRI contrast agent based on hybrid SPION@coordination polymer nanoparticles

We report a novel hybrid T-1/T-2 dual MRI contrast agent by the encapsulation of SPIONs (T-2 contrast agent) into an iron-based coordination polymer with T-1-weighted signal. This new hybrid material presents improved relaxometry and low cytotoxicity, which make it suitable for its use as contrast agent for MRI.