期刊
RUSSIAN CHEMICAL BULLETIN
卷 61, 期 12, 页码 2322-2325出版社
SPRINGER
DOI: 10.1007/s11172-012-0326-9
关键词
metal complex hydrogenation; 1-methyl-3,4-dihydroisoquinoline; amido-phosphite; iridium
A number of metal complex precatalysts, solvents, and additives were examined in the asymmetric hydrogenation of 1-methyl-3,4-dihydroisoquinoline in the presence of a chiral amidophosphite ligand. The enantioselectivity of hydrogenation of this substrate increased upon addition of iodine. The best result in the selective hydrogenation was observed when [Ir(COD)(2)]BARF was used as the precatalyst (COD is the cycloocta-1,5-diene, BARF is the tetrakis[3,5-bis(trifluoromethyl)phenyl]borate).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据