期刊
RUSSIAN CHEMICAL BULLETIN
卷 60, 期 11, 页码 2412-2417出版社
SPRINGER
DOI: 10.1007/s11172-011-0371-9
关键词
HPLC; H-1 and C-13 NMR; ROESY; HMBC; antibiotic; INA-1278; irumamycin
The screening for novel antibiotic producers by selection methods revealed the Streptomyces sp. strain No. 1278 producing the antibiotic INA-1278, which exhibits antimicrobial and antifungal activities. This compound was isolated from the liquid culture by extraction with organic solvents and purified by chromatographic methods. The structure of this antibiotic was studied by mass spectrometry and H-1 and C-13 NMR spectroscopy. An analysis of the results of the investigation indicate that the compound INA-1278 is structurally related to the antibiotic irumamycin, which has been studied earlier. However, the novel antibiotic may differ from irumamycin in the configurations of some asymmetric centers, which were not established at the present stage of our research.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据