4.1 Article

4-Methoxy-3-methylgoniothalamin from marine-derived fungi of the genus Penicillium

期刊

RUSSIAN CHEMICAL BULLETIN
卷 60, 期 4, 页码 760-763

出版社

SPRINGER
DOI: 10.1007/s11172-011-0117-8

关键词

marine-derived fungus Penicillium glabrum; Penicillium implicatum; styryl lactones; diphenyl ketones; protein Hsp70

资金

  1. Russian Foundation for Basic Research [09-04-00388, 08-04-00289]
  2. Presidium of the Russian Academy of Sciences
  3. Federal Agency for Science and Innovations of the Russian Federation [02.518.11.7169]
  4. Council on Grants of the President of the Russian Federation [NSh-3531.2010.4]

向作者/读者索取更多资源

The new styrylpyrone derivative, viz. 4-methoxy-3-methylgoniothalamin (1), and the known compound sulochrin were isolated from the marine-derived fungi Penicillium glabrum and P. implicatum. The structure of compound 1 was determined by X-ray diffraction, 2D NMR spectroscopy, and high-resolution mass spectrometry. It was shown for the first time that sulochrin increases expression of the protein Hsp70.

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