相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons
Hsien-Sung Huang et al.
NATURE (2012)
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
Farzaneh Modarresi et al.
NATURE BIOTECHNOLOGY (2012)
Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
Aubin Michalon et al.
NEURON (2012)
Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients
Christoph Laske et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2011)
Initial impact of the sequencing of the human genome
Eric S. Lander
NATURE (2011)
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
Tiffany Hung et al.
NATURE GENETICS (2011)
Non-coding RNAs in human disease
Manel Esteller
NATURE REVIEWS GENETICS (2011)
Targeted therapy for high-grade glioma with the TGF-beta 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
U. Bogdahn et al.
NEURO-ONCOLOGY (2011)
CTCF Regulates Ataxin-7 Expression through Promotion of a Convergently Transcribed, Antisense Noncoding RNA
Bryce L. Sopher et al.
NEURON (2011)
Enhancer of Zeste 2 (EZH2) is up-regulated in malignant gliomas and in glioma stem-like cells
F. Orzan et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2011)
lncRNAdb: a reference database for long noncoding RNAs
Paulo P. Amaral et al.
NUCLEIC ACIDS RESEARCH (2011)
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene
Y. Kotake et al.
ONCOGENE (2011)
Epigenetic Regulation of Gene Expression in Physiological and Pathological Brain Processes
Johannes Graeff et al.
PHYSIOLOGICAL REVIEWS (2011)
Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy
Marco A. Passini et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
GABAergic Circuit Development and Its Implication for CNS Disorders
Graziella Di Cristo et al.
NEURAL PLASTICITY (2011)
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation
Tim R. Mercer et al.
BMC NEUROSCIENCE (2010)
Long non-coding RNAs in nervous system function and disease
Irfan A. Qureshi et al.
BRAIN RESEARCH (2010)
MicroRNA dysregulation in psychiatric disease
Brooke H. Miller et al.
BRAIN RESEARCH (2010)
Brain-derived neurotrophic factor (BDNF) gene polymorphisms shape cortical plasticity in humans
Andrea Antal et al.
BRAIN STIMULATION (2010)
A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response
Maite Huarte et al.
CELL (2010)
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression
Delphine Bernard et al.
EMBO JOURNAL (2010)
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
Yimin Hua et al.
GENES & DEVELOPMENT (2010)
Partners in crime: bidirectional transcription in unstable microsatellite disease
Ranjan Batra et al.
HUMAN MOLECULAR GENETICS (2010)
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
Stephen M. Massa et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Angelman Syndrome, a Genomic Imprinting Disorder of the Brain
Stormy J. Chamberlain et al.
JOURNAL OF NEUROSCIENCE (2010)
Non-coding RNAs: regulators of disease
Ryan J. Taft et al.
JOURNAL OF PATHOLOGY (2010)
Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a
Kyoko L. Yap et al.
MOLECULAR CELL (2010)
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
Rajnish A. Gupta et al.
NATURE (2010)
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
Thomas Ernst et al.
NATURE GENETICS (2010)
Repeat instability as the basis for human diseases and as a potential target for therapy
Arturo Lopez Castel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Associations between Brain-Derived Neurotrophic Factor Plasma Levels and Severity of the Illness, Recurrence and Symptoms in Depressed Patients
Liliana Dell'Osso et al.
NEUROPSYCHOBIOLOGY (2010)
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear
Dennis C. Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
Miao-Chih Tsai et al.
SCIENCE (2010)
Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci
I-Cheng Chen et al.
BMC MOLECULAR BIOLOGY (2009)
Macrophage Delivery of Nanoformulated Antiretroviral Drug to the Brain in a Murine Model of NeuroAIDS
Huanyu Dou et al.
JOURNAL OF IMMUNOLOGY (2009)
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
Mitchell Guttman et al.
NATURE (2009)
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
Alan H. Nagahara et al.
NATURE MEDICINE (2009)
Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry
Allison M. Bond et al.
NATURE NEUROSCIENCE (2009)
Long non-coding RNAs: insights into functions
Tim R. Mercer et al.
NATURE REVIEWS GENETICS (2009)
Understanding microRNAs in neurodegeneration
Stephen M. Eacker et al.
NATURE REVIEWS NEUROSCIENCE (2009)
Differential Deployment of REST and CoREST Promotes Glial Subtype Specification and Oligodendrocyte Lineage Maturation
Joseph J. Abrajano et al.
PLOS ONE (2009)
Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth
Ahmed Hasbi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
Ahmad M. Khalil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
RNA Gain-of-Function in Spinocerebellar Ataxia Type 8
Randy S. Daughters et al.
PLOS GENETICS (2009)
Epigenetics and the Nervous System
Mark F. Mehler
ANNALS OF NEUROLOGY (2008)
A Novel H19 Antisense RNA Overexpressed in Breast Cancer Contributes to Paternal IGF2 Expression
Nathalie Berteaux et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation
Radha Raman Pandey et al.
MOLECULAR CELL (2008)
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
Wenqiang Yu et al.
NATURE (2008)
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
Xiangting Wang et al.
NATURE (2008)
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase
Mohammad Ali Faghihi et al.
NATURE MEDICINE (2008)
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163
Rintaro Hashizume et al.
NEURO-ONCOLOGY (2008)
A Novel RNA Transcript with Antiapoptotic Function Is Silenced in Fragile X Syndrome
Ahmad M. Khalil et al.
PLOS ONE (2008)
Divergent Transcription from Active Promoters
Amy C. Seila et al.
SCIENCE (2008)
The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin
Takashi Nagano et al.
SCIENCE (2008)
Transcription regulation through promoter-proximal pausing of RNA polymerase II
Leighton J. Core et al.
SCIENCE (2008)
The Antisense Transcriptomes of Human Cells
Yiping He et al.
SCIENCE (2008)
RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters
Pascal Preker et al.
SCIENCE (2008)
Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome
Jing Zhao et al.
SCIENCE (2008)
Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains
Manching Ku et al.
PLOS GENETICS (2008)
Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells
Kevin V. Morris et al.
PLOS GENETICS (2008)
Noncoding RNAs in Long-Term Memory Formation
Tim R. Mercer et al.
NEUROSCIENTIST (2008)
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals
Paula D. Ladd et al.
HUMAN MOLECULAR GENETICS (2007)
Genomic imprinting effects on brain development and function
Lawrence S. Wilkinson et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Engineering targeted viral vectors for gene therapy
Reinhard Waehler et al.
NATURE REVIEWS GENETICS (2007)
Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease
Mark F. Mehler et al.
PHYSIOLOGICAL REVIEWS (2007)
Functional demarcation of active and silent chromatin domains in human HOX loci by Noncoding RNAs
John L. Rinn et al.
CELL (2007)
Expandable DNA repeats and human disease
Sergei M. Mirkin
NATURE (2007)
Genome-wide mapping of in vivo protein-DNA interactions
David S. Johnson et al.
SCIENCE (2007)
RNA maps reveal new RNA classes and a possible function for pervasive transcription
Philipp Kapranov et al.
SCIENCE (2007)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
Antisense inhibition at the β-secretase-site of β-amyloid precursor protein reduces cerebral amyloid and acetyl cholinesterase activity in TG2576
Neelima B. Chauhan et al.
NEUROSCIENCE (2007)
Using attenuated salmonella typhi as tumor targeting vector for MDR1 siRNA delivery - An experimental study
Zhongming Jiang et al.
CANCER BIOLOGY & THERAPY (2007)
Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript
Igor Martianov et al.
NATURE (2007)
Localizing hotspots of antisense transcription
Giacomo Finocchiaro et al.
NUCLEIC ACIDS RESEARCH (2007)
Role of brain-derived neurotrophic factor in Huntington's disease
Chiara Zuccato et al.
PROGRESS IN NEUROBIOLOGY (2007)
The neuronal microRNA system
Kenneth S. Kosik
NATURE REVIEWS NEUROSCIENCE (2006)
Epigenetics of autism spectrum disorders
N. Carolyn Schanen
HUMAN MOLECULAR GENETICS (2006)
An RNA gene expressed during cortical development evolved rapidly in humans
Katherine S. Pollard et al.
NATURE (2006)
REST in good times and bad - Roles in tumor suppressor and oncogenic activities
Sadhan Majumder
CELL CYCLE (2006)
Antisense oligonucleotide therapy for neurodegenerative disease
Richard A. Smith et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8
Melinda L. Moseley et al.
NATURE GENETICS (2006)
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
Jianchi Feng et al.
GENES & DEVELOPMENT (2006)
Complex loci in human and mouse genomes
Par G. Engstrom et al.
PLOS GENETICS (2006)
Non-coding RNAs in the nervous system
Mark F. Mehler et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Imprinted genes, placental development and fetal growth
AL Fowden et al.
HORMONE RESEARCH (2006)
Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF
DH Cho et al.
MOLECULAR CELL (2005)
Repeat instability: Mechanisms of dynamic mutations
CE Pearson et al.
NATURE REVIEWS GENETICS (2005)
An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
Miaw-Chyi Luo et al.
MOLECULAR PAIN (2005)
Antisense transcription in the mammalian transcriptome
S Katayama et al.
SCIENCE (2005)
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
A Siepel et al.
GENOME RESEARCH (2005)
Imprinted gene expression in the brain
W Davies et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2005)
Bacterial ghosts as novel efficient targeting vehicles for DNA delivery to the human monocyte-derived dendritic cells
F Kudela et al.
JOURNAL OF IMMUNOTHERAPY (2005)
DNA-loaded bacterial ghosts efficiently mediate reporter gene transfer and expression in macrophages
S Paukner et al.
MOLECULAR THERAPY (2005)
Molecular signatures of natural selection
R Nielsen
ANNUAL REVIEW OF GENETICS (2005)
Virosomes for antigen and DNA delivery
T Daemen et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
Bacterial ghosts as novel advanced drug delivery systems: antiproliferative activity of loaded doxorubicin in human Caco-2 cells
S Paukner et al.
JOURNAL OF CONTROLLED RELEASE (2004)
Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference
DR Thakker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the National Institute of Mental Health Genetics Initiative pedigrees
TG Schulze et al.
BIOLOGICAL PSYCHIATRY (2004)
Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11
C Francks et al.
HUMAN MOLECULAR GENETICS (2003)
Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios
AG Clark et al.
SCIENCE (2003)
Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a
K Yarnasaki et al.
HUMAN MOLECULAR GENETICS (2003)
A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells
X Zhang et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Mouse brain gene expression changes after acute and chronic amphetamine
BP Sokolov et al.
JOURNAL OF NEUROCHEMISTRY (2003)
The RAY1/ST7 tumor-suppressor locus on chromosome 7q31 represents a complex multi-transcript system
JB Vincent et al.
GENOMICS (2002)
Expression of HIF-Iα by human macrophages:: implications for the use of macrophages in hypoxia-regulated cancer gene therapy
B Burke et al.
JOURNAL OF PATHOLOGY (2002)
CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease
R Ohlsson et al.
TRENDS IN GENETICS (2001)
Schizophrenia and affective disorders - Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: Clinical and P300 findings in a family
DHR Blackwood et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
SM Elbashir et al.
NATURE (2001)
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
P Lawinger et al.
NATURE MEDICINE (2000)
Disruption of two novel genes by a translocation co-segregating with schizophrenia
JK Millar et al.
HUMAN MOLECULAR GENETICS (2000)