期刊
RNA BIOLOGY
卷 9, 期 2, 页码 -出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/rna.18827
关键词
MicroRNA; miR-122; Pri-miRNA; GLD-2; CAT-1; Cholesterol; Hepatitis C virus
资金
- BBSRC [BB/F02360X/1]
- BBSRC [BB/F02360X/1] Funding Source: UKRI
microRNA-122 (miR-122) was one of the first examples of a tissue-specific miRNA. It is highly expressed in liver, where it constitutes 70% of the total miRNA pool. miR-122 expression is specific to the vertebrate lineage, where the sequence of the mature miRNA is completely conserved. miR-122 is a target for extensive study due to its association with cholesterol metabolism and hepatocellular carcinoma, and its important role in promoting hepatitis C virus (HCV) replication. This review will discuss the biogenesis and function of miR-122.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据