期刊
RNA BIOLOGY
卷 8, 期 5, 页码 728-734出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/rna.8.5.16324
关键词
miR-10; miR-100; HOX genes; cancer; retinoic acid; evolution
资金
- Danish National Research Foundation
- EC FP7 ONCOMIRS consortium [201102]
- Novo Nordisk Foundation
- Lundbeck Foundation
- Danish Cancer Society
- Danish National Advanced Technology Foundation
- Lundbeck Foundation [R31-2007-1447] Funding Source: researchfish
The miR-10 microRNA precursor family encodes a group of short non-coding RNAs involved in gene regulation. The miR-10 family is highly conserved and has sparked the interest of many research groups because of the genomic localization in the vicinity of, coexpression with and regulation of the Hox gene developmental regulators. Here, we review the current knowledge of the evolution, physiological function and involvement in cancer of this family of microRNAs.
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