期刊
RNA BIOLOGY
卷 7, 期 1, 页码 104-110出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/rna.7.1.10757
关键词
transcription attenuation; antitermination; translation control; RNA aptamer; regulation
资金
- National Institutes of Health [GM47823, GM63615]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM063615, R01GM047823] Funding Source: NIH RePORTER
Riboswitches are cis-encoded, cis-acting RNA elements that directly sense a physiological signal. Signal response results in a change in RNA structure that impacts gene expression. Elements of this type play an important role in bacteria, where they regulate a variety of fundamental cellular pathways. Riboswitch- mediated gene regulation most commonly occurs by effects on transcription attenuation, to control whether a full-length transcript is synthesized, or on translation initiation, in which case the transcript is constitutively synthesized but binding of the translation initiation complex is modulated. An overview of the role of riboswitch RNAs in bacterial gene expression will be provided, and a few examples are described in more detail to illustrate the types of mechanisms that have been uncovered.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据